Tretinoin 0.05% Gel is a dermatologist-approved retinoid formulated for oily and acne-prone skin. The lightweight gel base penetrates quickly to clear breakouts, refine rough texture and soften early fine lines.

Designed for night use only, it must be paired with daily SPF to protect new, refreshed skin under.

Key benefits of Tretinoin 0.05% Gel

• Unclogs pores and cuts new breakouts

• Smooths rough texture and softens fine lines for anti-wrinkle care

• Fades dark marks and supports a more even tone

• 0.05% strength is a smart step up from 0.025% for steady progress

• Lightweight gel base absorbs fast and leaves low residue, making it ideal for oily or combination skin

  
  

Who is Tretinoin 0.05% Gel for

• Best for acne-prone, oily, or combination skin types; perfect for those progressing from 0.025%

• Not for pregnancy or breastfeeding, active eczema, rosacea flare-ups or broken and irritated skin

• Must apply broad-spectrum SPF 30+ daily to protect new skin

  
  

How to use Tretinoin 0.05% Gel

• Cleanse your face gently and let the skin dry completely

• Apply a pea-sized amount evenly across the full face in a thin layer at night

• Start slow: Use 2–3 nights per week, then build to nightly as your skin adapts

• Follow with a light, non-comedogenic moisturizer to prevent dryness

• Use SPF every morning to protect against sun sensitivity

Note: Mild dryness or peeling may appear during the first few weeks. Avoid applying near the eyes, nostrils and mouth corners.

What to expect from Tretinoin 0.05% Gel

• Weeks 1–3: Mild dryness or a short purge phase may occur as your skin adjusts

• Weeks 4–8: Texture feels smoother with fewer new breakouts and less congestion

• 3–6 months: Skin tone appears clearer, and post-blemish marks begin to fade with steady use